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Observe Intently (one)pentobarbital will reduce the extent or effect of cannabidiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the extent or influence of celecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Small/Significance Unidentified.pentobarbital will reduce the level or outcome of zaleplon by im